Proven results with COBENFY™

(xanomeline and trospium chloride)

Sagan is taking COBENFY. Sagan was compensated for his time.

COBENFY improved schizophrenia symptoms

Studied in three 5-week and two 52-week clinical studies with more than 1250 adults with schizophrenia.

In 2 clinical studies,* COBENFY showed...

Icon

Proven significant symptom relief vs placebo (sugar pill)

Icon

Overall improvement
across a range of symptoms*

A infographic defining positive and negative symptoms of schizophrenia

*A schizophrenia rating scale was used to compare meaningful changes in symptoms overall. These symptoms included positive, negative, and general psychopathology symptoms.

In 1 clinical study, COBENFY...
Icon

Reduced the overall
severity of schizophrenia

A different schizophrenia rating tool was used to evaluate meaningful overall changes in the severity of schizophrenia.

COBENFY was studied in two 5-week clinical studies with 470 adults aged 18 to 65 diagnosed with schizophrenia. Participants either took COBENFY or a sugar pill. Individual results may vary.

Two dark-haired women sit in chairs next to each other, one listening intently to the other
Two dark-haired women sit in chairs next to each other, one listening intently to the other
Two dark-haired women sit in chairs next to each other, one listening intently to the other

Start the COBENFY conversation with your healthcare provider

The Doctor Discussion Guide helps you create a list of questions for your next appointment.

Actor portrayals.

Kelsey is not taking COBENFY. Kelsey and Jia have been compensated for their time.



Cobenfy, Cobenfy Cares, and the Cobenfy logo are trademarks of Karuna Therapeutics, Inc., a Bristol Myers Squibb company.
© 2025 Bristol-Myers Squibb Company. 
1629-US-2500777 08/25
This website is intended for U.S. residents 18 years of age or older.