Real people, real stories

Meet amazing people sharing personal stories about their journeys living with schizophrenia

Chanel is taking COBENFY. Chanel and Fines were compensated for their time.

Support starts with connection

Watch these three videos to hear real experiences from people living with schizophrenia and their care partners, along with guidance from a healthcare provider on the importance of advocating for yourself.

Thumbnail from video featuring Avary, an actual COBENFY (xanomeline and trospium chloride) patient, with his wife Ashleigh

Avary and Ashleigh: Navigating together

Avary, who has schizophrenia, and his wife and care partner, Ashleigh, share how they navigate his diagnosis together—supporting one another through challenges, open communication, and his journey to finding COBENFY.

I’ve always thought that sitting at the table together is the best way to find comfort and talk to each other, open up and have conversations that are often hard to have in any other setting. I’m Gail Simmons, and today I’m preparing a meal for a group of people living with schizophrenia, their care partners, and Doctor Ares-Romero.

Hi, I’m Avary. I’m living with schizophrenia.

I’m Ashleigh, and I’m Avary’s wife and care partner.

I had a brother who was diagnosed with schizophrenia in his mid-20s. I was a teenager, and so this was something I had really never heard about and really didn’t understand. And I have this very clear memory of sitting with the doctor and them saying, “You really have to think of it as a medical diagnosis and a disease. What he needs is care and treatment.” So Avary, I’d love to hear your story. Your experience with schizophrenia. Do you remember the first day of your schizophrenia diagnosis?

I was angry at myself, and I was really sad. I literally thought, you know, my life was over. It’s like you don’t know what comes next after a diagnosis like that. I remember I was in a tough spot. I felt like I had nobody, because with the illness, it feels like you’re alone. I just felt like once I received the diagnosis, I didn’t have, like, hope. Having someone to lean on like Ashleigh, you know, she’s been with me the past seven years, and just actually, you know, physically being able to rub my back or be there to talk to me. It’s just a reassuring feeling.

Avary, how important has it been to find the right treatment path and support, and ultimately to find COBENFY?

Overall, the journey that I’ve had and the support that I have is unwavering to everything that I am today. My doctor that I have now, he actually listened to me. He still listens to me. When he introduced COBENFY to me, I just decided, you know, let’s give it a shot. My doctor talked to me about some possible side effects such as nausea, stomach upset and others. At the end of the day, I look at it and say, I am so lucky to have what I have and have the people around me. And I’m just, I’m blessed.

I think connection can be so many things. It can be, you know, obviously speaking, sharing your thoughts, your emotions. It can be a great meal. Because I think there’s a universal humanity in all of these things. And I think they are what connect us.

I’m lucky to be here.

We feel lucky to have you.

We will now review Important Safety Information. Please see the top of this webpage for links to Patient Information and full Prescribing Information for COBENFY.

COBENFY™ (xanomeline and trospium chloride) is a prescription medicine used to treat schizophrenia in adults. It is not known if COBENFY is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take COBENFY if you:

  • have urinary retention problems that cause your bladder to not empty completely or not empty at all
  • have moderate or severe liver problems (impairment)
  • have gastric retention problems that cause your stomach to empty slowly
  • are allergic to COBENFY, xanomeline, or trospium chloride, or any of the ingredients in COBENFY
  • have an eye problem called untreated narrow-angle glaucoma

Before taking COBENFY, tell your healthcare provider about all of your medical conditions, including if you:

  • have an enlarged prostate, problems passing urine, or a blockage in your urinary bladder
  • have liver problems
  • have or have had gallstones or problems with your bile ducts or pancreas
  • have stomach or intestinal problems, including constipation, ulcerative colitis, slow emptying of your stomach, or myasthenia gravis
  • have an eye condition called narrow-angle glaucoma
  • have kidney problems
  • are pregnant or plan to become pregnant. It is not known if COBENFY may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you are pregnant during treatment with COBENFY.
    • There is a pregnancy exposure registry for women who take COBENFY during pregnancy. The purpose of this registry is to collect information about the health of women exposed to COBENFY and their baby. If you become pregnant during treatment with COBENFY, your healthcare provider will register you by calling 1-866-961-2388 or online at https://womensmentalhealth.org/research/pregnancyregistry/atypicalantipsychotic/
  • are breastfeeding or plan to breastfeed. It is not known if COBENFY passes into your breast milk or if it can harm your baby

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking COBENFY with certain other medicines may increase your risk of side effects from COBENFY or the other medicine and may affect the way COBENFY or the other medicine works. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What should I avoid while taking COBENFY?
Do not drive, operate heavy machinery, or do other dangerous activities until you know how COBENFY affects you. COBENFY may cause dizziness, confusion, seeing or hearing things that are not real (hallucinations), and sleepiness.

COBENFY may cause serious side effects, including:

  • Problems with emptying your bladder (urinary retention). See “Do not take COBENFY if you:” COBENFY may cause your bladder to not empty completely or not empty at all. You are at increased risk for urinary retention if you are elderly, have a blockage in your bladder, have an enlarged prostate called benign prostatic hyperplasia (BPH), have bladder emptying problems from diabetes, or are taking higher doses of COBENFY. Urinary retention may increase your risk for getting a urinary tract infection. Call your healthcare provider or get emergency help right away if you get any signs or symptoms of urinary retention during treatment with COBENFY, including:
    • difficulty urinating
    • urination in a weak stream or drips
    • urinating frequently
    • full bladder and difficulty emptying your bladder
    • pain when you urinate
  • Risks in people with liver problems. See “Do not take COBENFY if you:” It is not recommended that people with mild liver problems (impairment) take COBENFY because they have an increased risk of getting side effects from COBENFY. Your healthcare provider will check the liver enzyme levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of liver problems during treatment with COBENFY, including:
    • yellowing of your skin or the white part of your eyes
    • dark urine
    • pain and swelling in the upper right part of your stomach (abdomen)
    • stomach pain that spreads to your back or to below your right shoulder
    • itching
    • nausea or vomiting
    • loss of appetite
    • fever
    • chills
    • light-colored stools
    • tiredness
  • Risks in people with bile duct and gallbladder problems (biliary disease). COBENFY may cause a blockage in your bile ducts that could lead to gallstones, pancreatitis, and increases in your liver enzymes. Your healthcare provider will check your liver enzyme and bilirubin levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of biliary disorders during treatment with COBENFY, including:
    • stomach upset or burning (dyspepsia)
    • nausea
    • vomiting
    • pain in the upper right part of your stomach
  • Slow emptying of your stomach (decreased gastrointestinal motility). See “Do not take COBENFY if you:” You are at increased risk for getting decreased gastrointestinal motility if you have ulcerative colitis, already have problems with slow stomach emptying, and have myasthenia gravis. Tell your healthcare provider if you get any signs and symptoms of decreased gastrointestinal motility during treatment with COBENFY, including:
    • constipation
    • vomiting
    • nausea
    • stomach (abdominal) bloating
    • stomach (abdominal) pain
    • a feeling of fullness after eating just a few bites
    • acid reflux
  • Serious allergic reactions (angioedema). Angioedema may happen during treatment with COBENFY and can be life threatening. Stop taking COBENFY and call your healthcare provider or get emergency help right away if you get any of the following signs or symptoms of a serious allergic reaction during treatment with COBENFY, including:
    • hives
    • swelling of your face, lips, mouth, or tongue
    • swelling of your throat
    • hoarseness or difficulty speaking
    • breathing problems
  • An eye problem called narrow-angle glaucoma. See “Do not take COBENFY if you:” If you already have narrow angles in your eyes, COBENFY may cause a sudden attack (acute angle closure) of glaucoma. Tell your healthcare provider if you get any signs or symptoms of narrow-angle glaucoma during treatment with COBENFY, including:
    • red eyes
    • blurred vision
    • seeing halos or bright colors around lights
    • eye pain or discomfort
    • nausea or vomiting
    • severe headache
  • Increases in heart rate. COBENFY may increase your heart (pulse) rate. Your healthcare provider should check your heart rate before you start treatment and during treatment as needed. Tell your healthcare provider if you get a racing or pounding feeling in your chest during treatment with COBENFY.

  • Side effects in people with kidney problems. People with kidney problems may have an increased risk of getting dry mouth, constipation, stomach upset or burning, urinary tract infection, and urinary retention during treatment with COBENFY.

  • Central nervous system problems. See “What should I avoid while taking COBENFY?”

The most common side effects of COBENFY include:

  • nausea
  • stomach upset or burning (dyspepsia)
  • constipation
  • vomiting
  • high blood pressure
  • stomach (abdominal) pain
  • diarrhea
  • increased heart rate
  • dizziness
  • heartburn (gastrointestinal reflux disease)

Your healthcare provider may lower your dose or stop treatment with COBENFY if you get certain side effects.

These are not all of the possible side effects of COBENFY.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the Full Prescribing Information, including Patient Information at www.cobenfy.com or click the buttons at the top of this webpage.

Avary is sharing his individual experiences; Avary and Ashleigh were compensated for their time. Results may vary.

Thumbnail from video featuring Chanel, an actual COBENFY (xanomeline and trospium chloride) patient, with her mom Fines

Chanel and Fines: Standing by each other

Chanel and her mother and care partner, Fines, share how their strong bond helps them navigate Chanel’s journey with schizophrenia—supporting each other through challenges and sharing her experience with COBENFY.

My brother was diagnosed with schizophrenia when he was in his mid-20s. He was my biggest, best cheerleader and my big brother. And so, there was a lot of sort of reevaluating of our relationship and understanding what he was going through or trying my best to understand what he was going through. I think cooking and eating together, especially when you can sit down at a table with loved ones, but also strangers, really, anyone. Sitting down at the table together for me really gives you a sense of comfort, a sense of community.

It feels nice. I can like, being at a table with my whole family. It feels, I feel supported, I know I’m not alone when I sit down at that table. My name is Chanel. This is my mother. She has helped me through my whole journey.

My name is Fines. This is my daughter, Chanel, and I am her caregiver.

It actually took me a while to find support in my mother. She’s always been there for me, but I started realizing I could confide in her. I could trust her, that she was my support and that she was always my support.

You can be there even if you don’t have the answer. You can help them search for the answer, and take time for yourself, you know, like, try to remember that, like you’re not Superwoman. You’re not Superman. We had been through a lot of different, you know, psychiatrists and doctors, trying to find help for her.

And finding treatment – how did you get there?

Lots of research, lots of reading. There’s a medication, you know, and it’s different.

Since starting COBENFY, I’ve seen an improvement in my overall schizophrenia symptoms. My doctor also talked to me about possible side effects such as nausea, stomach upset, and others. I couldn’t do this without medication or the support of my mother.

If you don’t feel like your doctor is listening to you, don’t give up. Find a different doctor. The important part is to not give up.

We will now review Important Safety Information. Please see the top of this webpage for links to Patient Information and full Prescribing Information for COBENFY.

COBENFY™ (xanomeline and trospium chloride) is a prescription medicine used to treat schizophrenia in adults. It is not known if COBENFY is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take COBENFY if you:

  • have urinary retention problems that cause your bladder to not empty completely or not empty at all
  • have moderate or severe liver problems (impairment)
  • have gastric retention problems that cause your stomach to empty slowly
  • are allergic to COBENFY, xanomeline, or trospium chloride, or any of the ingredients in COBENFY
  • have an eye problem called untreated narrow-angle glaucoma

Before taking COBENFY, tell your healthcare provider about all of your medical conditions, including if you:

  • have an enlarged prostate, problems passing urine, or a blockage in your urinary bladder
  • have liver problems
  • have or have had gallstones or problems with your bile ducts or pancreas
  • have stomach or intestinal problems, including constipation, ulcerative colitis, slow emptying of your stomach, or myasthenia gravis
  • have an eye condition called narrow-angle glaucoma
  • have kidney problems
  • are pregnant or plan to become pregnant. It is not known if COBENFY may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you are pregnant during treatment with COBENFY.
    • There is a pregnancy exposure registry for women who take COBENFY during pregnancy. The purpose of this registry is to collect information about the health of women exposed to COBENFY and their baby. If you become pregnant during treatment with COBENFY, your healthcare provider will register you by calling 1-866-961-2388 or online at https://womensmentalhealth.org/research/pregnancyregistry/atypicalantipsychotic/
  • are breastfeeding or plan to breastfeed. It is not known if COBENFY passes into your breast milk or if it can harm your baby

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking COBENFY with certain other medicines may increase your risk of side effects from COBENFY or the other medicine and may affect the way COBENFY or the other medicine works. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What should I avoid while taking COBENFY?
Do not drive, operate heavy machinery, or do other dangerous activities until you know how COBENFY affects you. COBENFY may cause dizziness, confusion, seeing or hearing things that are not real (hallucinations), and sleepiness.

COBENFY may cause serious side effects, including:

  • Problems with emptying your bladder (urinary retention). See “Do not take COBENFY if you:” COBENFY may cause your bladder to not empty completely or not empty at all. You are at increased risk for urinary retention if you are elderly, have a blockage in your bladder, have an enlarged prostate called benign prostatic hyperplasia (BPH), have bladder emptying problems from diabetes, or are taking higher doses of COBENFY. Urinary retention may increase your risk for getting a urinary tract infection. Call your healthcare provider or get emergency help right away if you get any signs or symptoms of urinary retention during treatment with COBENFY, including:
    • difficulty urinating
    • urination in a weak stream or drips
    • urinating frequently
    • full bladder and difficulty emptying your bladder
    • pain when you urinate
  • Risks in people with liver problems. See “Do not take COBENFY if you:” It is not recommended that people with mild liver problems (impairment) take COBENFY because they have an increased risk of getting side effects from COBENFY. Your healthcare provider will check the liver enzyme levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of liver problems during treatment with COBENFY, including:
    • yellowing of your skin or the white part of your eyes
    • dark urine
    • pain and swelling in the upper right part of your stomach (abdomen)
    • stomach pain that spreads to your back or to below your right shoulder
    • itching
    • nausea or vomiting
    • loss of appetite
    • fever
    • chills
    • light-colored stools
    • tiredness
  • Risks in people with bile duct and gallbladder problems (biliary disease). COBENFY may cause a blockage in your bile ducts that could lead to gallstones, pancreatitis, and increases in your liver enzymes. Your healthcare provider will check your liver enzyme and bilirubin levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of biliary disorders during treatment with COBENFY, including:
    • stomach upset or burning (dyspepsia)
    • nausea
    • vomiting
    • pain in the upper right part of your stomach
  • Slow emptying of your stomach (decreased gastrointestinal motility). See “Do not take COBENFY if you:” You are at increased risk for getting decreased gastrointestinal motility if you have ulcerative colitis, already have problems with slow stomach emptying, and have myasthenia gravis. Tell your healthcare provider if you get any signs and symptoms of decreased gastrointestinal motility during treatment with COBENFY, including:
    • constipation
    • vomiting
    • nausea
    • stomach (abdominal) bloating
    • stomach (abdominal) pain
    • a feeling of fullness after eating just a few bites
    • acid reflux
  • Serious allergic reactions (angioedema). Angioedema may happen during treatment with COBENFY and can be life threatening. Stop taking COBENFY and call your healthcare provider or get emergency help right away if you get any of the following signs or symptoms of a serious allergic reaction during treatment with COBENFY, including:
    • hives
    • swelling of your face, lips, mouth, or tongue
    • swelling of your throat
    • hoarseness or difficulty speaking
    • breathing problems
  • An eye problem called narrow-angle glaucoma. See “Do not take COBENFY if you:” If you already have narrow angles in your eyes, COBENFY may cause a sudden attack (acute angle closure) of glaucoma. Tell your healthcare provider if you get any signs or symptoms of narrow-angle glaucoma during treatment with COBENFY, including:
    • red eyes
    • blurred vision
    • seeing halos or bright colors around lights
    • eye pain or discomfort
    • nausea or vomiting
    • severe headache
  • Increases in heart rate. COBENFY may increase your heart (pulse) rate. Your healthcare provider should check your heart rate before you start treatment and during treatment as needed. Tell your healthcare provider if you get a racing or pounding feeling in your chest during treatment with COBENFY.

  • Side effects in people with kidney problems. People with kidney problems may have an increased risk of getting dry mouth, constipation, stomach upset or burning, urinary tract infection, and urinary retention during treatment with COBENFY.

  • Central nervous system problems. See “What should I avoid while taking COBENFY?”

The most common side effects of COBENFY include:

  • nausea
  • stomach upset or burning (dyspepsia)
  • constipation
  • vomiting
  • high blood pressure
  • stomach (abdominal) pain
  • diarrhea
  • increased heart rate
  • dizziness
  • heartburn (gastrointestinal reflux disease)

Your healthcare provider may lower your dose or stop treatment with COBENFY if you get certain side effects.

These are not all of the possible side effects of COBENFY.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the Full Prescribing Information, including Patient Information at www.cobenfy.com or click the buttons at the top of this webpage.

Chanel is sharing her individual experiences; Chanel and Fines were compensated for their time. Results may vary.

Thumbnail from video featuring Dr. Patricia Ares-Romero, a board-certified psychiatrist

Dr Ares-Romero: Be your own advocate

Dr Ares-Romero discusses the role of self-advocacy and open communication with healthcare providers, sharing guidance on speaking up about symptoms, goals, and treatment preferences when managing schizophrenia.

I didn’t feel heard. I didn’t feel seen, like, what am I supposed to tell them? Another thing, they’re not going to believe me on?

Right.

I literally saw my doctor for maybe five minutes. I wasn’t really listened to. My doctor that I have now, he actually listens to me. He still listens to me.

If a doctor shuts you down, we should all be able to advocate for ourselves and say, hey, listen, you know, I disagree with this, or let’s have a discussion, or what are my options, I’m concerned about A, B, C or D.

My name is Patricia Ares-Romero, and I’m a board-certified psychiatrist. Many times, not only the diagnosis is delayed, but the correct treatment, right, is delayed. And that’s the key.

I had a brother who was diagnosed with schizophrenia in his mid-20s. My brother’s diagnosis affected my family in a million ways. Trying to find the right treatment for him and to get him the help he needed, even when he didn’t want it, which was a really big part of the struggle.

The importance with patients, they really need to be honest with their symptoms. And only when we know about these symptoms are we able to treat them appropriately.

Because there’s such a broad range of symptoms, that schizophrenia is such an umbrella, meaning so many different things and manifesting in so many ways, that it’s hard also to explain your symptoms clearly because they are so challenging and so complicated.

This is why it’s so important for me to meet with a patient, meet with the family, and kind of really understand what other symptoms they may be experiencing that maybe they haven’t told me about.

I imagine it takes a lot of courage, but I also imagine it’s incredibly important to be able to have these really honest conversations with your healthcare providers.

If a family comes to my office and says, listen, you know, we found out about this medication or this is going on, I think it’s so important. It’s very easy to be isolated and withdrawn when you’re struggling with a disease that’s so complex, and having that connection, with family, with friends, with community, with providers, inclusive, really helps together with the right treatment.

We will now review Important Safety Information. Please see the top of this webpage for links to Patient Information and full Prescribing Information for COBENFY.

COBENFY™ (xanomeline and trospium chloride) is a prescription medicine used to treat schizophrenia in adults. It is not known if COBENFY is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take COBENFY if you:

  • have urinary retention problems that cause your bladder to not empty completely or not empty at all
  • have moderate or severe liver problems (impairment)
  • have gastric retention problems that cause your stomach to empty slowly
  • are allergic to COBENFY, xanomeline, or trospium chloride, or any of the ingredients in COBENFY
  • have an eye problem called untreated narrow-angle glaucoma

Before taking COBENFY, tell your healthcare provider about all of your medical conditions, including if you:

  • have an enlarged prostate, problems passing urine, or a blockage in your urinary bladder
  • have liver problems
  • have or have had gallstones or problems with your bile ducts or pancreas
  • have stomach or intestinal problems, including constipation, ulcerative colitis, slow emptying of your stomach, or myasthenia gravis
  • have an eye condition called narrow-angle glaucoma
  • have kidney problems
  • are pregnant or plan to become pregnant. It is not known if COBENFY may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you are pregnant during treatment with COBENFY.
    • There is a pregnancy exposure registry for women who take COBENFY during pregnancy. The purpose of this registry is to collect information about the health of women exposed to COBENFY and their baby. If you become pregnant during treatment with COBENFY, your healthcare provider will register you by calling 1-866-961-2388 or online at https://womensmentalhealth.org/research/pregnancyregistry/atypicalantipsychotic/
  • are breastfeeding or plan to breastfeed. It is not known if COBENFY passes into your breast milk or if it can harm your baby

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking COBENFY with certain other medicines may increase your risk of side effects from COBENFY or the other medicine and may affect the way COBENFY or the other medicine works. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What should I avoid while taking COBENFY?
Do not drive, operate heavy machinery, or do other dangerous activities until you know how COBENFY affects you. COBENFY may cause dizziness, confusion, seeing or hearing things that are not real (hallucinations), and sleepiness.

COBENFY may cause serious side effects, including:

  • Problems with emptying your bladder (urinary retention). See “Do not take COBENFY if you:” COBENFY may cause your bladder to not empty completely or not empty at all. You are at increased risk for urinary retention if you are elderly, have a blockage in your bladder, have an enlarged prostate called benign prostatic hyperplasia (BPH), have bladder emptying problems from diabetes, or are taking higher doses of COBENFY. Urinary retention may increase your risk for getting a urinary tract infection. Call your healthcare provider or get emergency help right away if you get any signs or symptoms of urinary retention during treatment with COBENFY, including:
    • difficulty urinating
    • urination in a weak stream or drips
    • urinating frequently
    • full bladder and difficulty emptying your bladder
    • pain when you urinate
  • Risks in people with liver problems. See “Do not take COBENFY if you:” It is not recommended that people with mild liver problems (impairment) take COBENFY because they have an increased risk of getting side effects from COBENFY. Your healthcare provider will check the liver enzyme levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of liver problems during treatment with COBENFY, including:
    • yellowing of your skin or the white part of your eyes
    • dark urine
    • pain and swelling in the upper right part of your stomach (abdomen)
    • stomach pain that spreads to your back or to below your right shoulder
    • itching
    • nausea or vomiting
    • loss of appetite
    • fever
    • chills
    • light-colored stools
    • tiredness
  • Risks in people with bile duct and gallbladder problems (biliary disease). COBENFY may cause a blockage in your bile ducts that could lead to gallstones, pancreatitis, and increases in your liver enzymes. Your healthcare provider will check your liver enzyme and bilirubin levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of biliary disorders during treatment with COBENFY, including:
    • stomach upset or burning (dyspepsia)
    • nausea
    • vomiting
    • pain in the upper right part of your stomach
  • Slow emptying of your stomach (decreased gastrointestinal motility). See “Do not take COBENFY if you:” You are at increased risk for getting decreased gastrointestinal motility if you have ulcerative colitis, already have problems with slow stomach emptying, and have myasthenia gravis. Tell your healthcare provider if you get any signs and symptoms of decreased gastrointestinal motility during treatment with COBENFY, including:
    • constipation
    • vomiting
    • nausea
    • stomach (abdominal) bloating
    • stomach (abdominal) pain
    • a feeling of fullness after eating just a few bites
    • acid reflux
  • Serious allergic reactions (angioedema). Angioedema may happen during treatment with COBENFY and can be life threatening. Stop taking COBENFY and call your healthcare provider or get emergency help right away if you get any of the following signs or symptoms of a serious allergic reaction during treatment with COBENFY, including:
    • hives
    • swelling of your face, lips, mouth, or tongue
    • swelling of your throat
    • hoarseness or difficulty speaking
    • breathing problems
  • An eye problem called narrow-angle glaucoma. See “Do not take COBENFY if you:” If you already have narrow angles in your eyes, COBENFY may cause a sudden attack (acute angle closure) of glaucoma. Tell your healthcare provider if you get any signs or symptoms of narrow-angle glaucoma during treatment with COBENFY, including:
    • red eyes
    • blurred vision
    • seeing halos or bright colors around lights
    • eye pain or discomfort
    • nausea or vomiting
    • severe headache
  • Increases in heart rate. COBENFY may increase your heart (pulse) rate. Your healthcare provider should check your heart rate before you start treatment and during treatment as needed. Tell your healthcare provider if you get a racing or pounding feeling in your chest during treatment with COBENFY.

  • Side effects in people with kidney problems. People with kidney problems may have an increased risk of getting dry mouth, constipation, stomach upset or burning, urinary tract infection, and urinary retention during treatment with COBENFY.

  • Central nervous system problems. See “What should I avoid while taking COBENFY?”

The most common side effects of COBENFY include:

  • nausea
  • stomach upset or burning (dyspepsia)
  • constipation
  • vomiting
  • high blood pressure
  • stomach (abdominal) pain
  • diarrhea
  • increased heart rate
  • dizziness
  • heartburn (gastrointestinal reflux disease)

Your healthcare provider may lower your dose or stop treatment with COBENFY if you get certain side effects.

These are not all of the possible side effects of COBENFY.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the Full Prescribing Information, including Patient Information at www.cobenfy.com or click the buttons at the top of this webpage.

Dr Ares-Romero was compensated for her time.

Real conversations about schizophrenia

Meet patients living with schizophrenia and learn how they navigate the various aspects of their journey.

The people featured in these videos are sharing their individual experiences with schizophrenia. Not all of those featured are currently taking COBENFY. Individual experiences with the condition and treatment may vary.

Older woman in a white shirt and brown cardigan looking into the camera

Jia is not taking COBENFY and was compensated for her time.

Supporting a loved one

Watch Jia discuss how she supports her daughter, Kelsey, and the importance of feeling supported herself.

Brunette woman in a green shirt smiling into the camera

Chayilee is not taking COBENFY and was compensated for her time.

Personal strategies

Watch real stories about how daily habits and hobbies can make a big difference in managing schizophrenia.

Older man with glasses and a salt-and-pepper colored beard looking into the camera

Albert is taking COBENFY and was compensated for his time.

Being supported

Hear how real people with schizophrenia find ways to feel supported and what it means to them.

Wavy-haired woman in a pink shirt looking into the camera

Kelsey is not taking COBENFY and was compensated for her time.

Starting conversations

People living with schizophrenia share the importance of having open conversations with their healthcare providers—and different ways they’ve approached it.

/

Take your next step with COBENFY

Get ready for your next appointment

Check out the COBENFY Discussion Guide to help you make the most of your next appointment.

Dive into COBENFY results

Explore how COBENFY performed in 2 clinical studies of patients living with schizophrenia.

Share your story

People living with schizophrenia want to hear your experiences with COBENFY.

Albert is taking COBENFY and was compensated for his time.



1629-US-2501134 10/25

1629-US-2600198 03/26

Cobenfy, Cobenfy Cares, and the Cobenfy logo are trademarks of Karuna Therapeutics, Inc., a Bristol Myers Squibb company.
© 2026 Bristol-Myers Squibb Company.
1629-US-2600153 03/26
1629-US-2600035 01/26
This website is intended for U.S. residents 18 years of age or older.